Adiponectin as an anti-inflammatory factor
نویسندگان
چکیده
منابع مشابه
Adiponectin acts as an endogenous antithrombotic factor.
OBJECTIVE Obesity is a common risk factor in insulin resistance and cardiovascular diseases. Although hypoadiponectinemia is associated with obesity-related metabolic and vascular diseases, the role of adiponectin in thrombosis remains elusive. METHODS AND RESULTS We investigated platelet thrombus formation in adiponectin knockout (APN-KO) male mice (8 to 12 weeks old) fed on a normal diet. T...
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Altered macrophage kinetics is a pivotal mechanism of visceral obesity-induced inflammation and cardiometabolic risk. Because monocytes can differentiate into either proatherogenic M1 macrophages or anti-inflammatory M2 macrophages, approaches that limit M1 while promoting M2 differentiation represent a unique therapeutic strategy. We hypothesized that adiponectin may prime human monocytes towa...
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ژورنال
عنوان ژورنال: Clinica Chimica Acta
سال: 2007
ISSN: 0009-8981
DOI: 10.1016/j.cca.2007.01.026